Publications

La plateforme H2P2 a organisé 2 congrès en 2010 et 2013. Nous sommes régulièrement associés aux publications des équipes de recherche, auxquels nous apportons notre expertise technologique. Etre cité dans les remerciements est également un encouragement pour toute l'équipe et une reconnaissance de notre savoir-faire.

Congrès de l'AFH à Rennes
  1. Publications
  2. Remerciements

Publications

2017

Validation of a New Scoring Scale for Behavioral Assessment of L-Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development.
Loiodice S, Denibaud AS, Deffains W, Alix M, Montagne P, Seffals M, Drieu La Rochelle C.
ACS Chem Neurosci. 2017 Dec 22. doi: 10.1021/acschemneuro.7b00426. [Epub ahead of print]
PMID: 29226687

Validating Missing Proteins in Human Sperm Cells by Targeted Mass-Spectrometry- and Antibody-based Methods.
Carapito C, Duek P, Macron C, Seffals M, Rondel K, Delalande F, Lindskog C, Fréour T, Vandenbrouck Y, Lane L, Pineau C.
J Proteome Res. 2017 Dec 1;16(12):4340-4351. doi: 10.1021/acs.jproteome.7b00374. Epub 2017 Sep 26.
PMID: 28891297

An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes.
Levet S, Medina J, Joanou J, Demolder A, Queruel N, Réant K, Normand M, Seffals M, Dimier J, Germi R, Piofczyk T, Portoukalian J, Touraine JL, Perron H.
JCI Insight. 2017 Sep 7;2(17). pii: 94387. doi: 10.1172/jci.insight.94387. [Epub ahead of print]
PMID: 28878130

Thymoquinone prevents endoplasmic reticulum stress and mitochondria-induced apoptosis in a rat model of partial hepatic warm ischemia reperfusion.
Bouhlel A, Ben Mosbah I, Hadj Abdallah N, Ribault C, Viel R, Mannaï S, Corlu A, Ben Abdennebi H.
Biomed Pharmacother. 2017 Oct;94:964-973. doi: 10.1016/j.biopha.2017.08.018. Epub 2017 Aug 12.
PMID: 28810534

Propolis reversed cigarette smoke-induced emphysema through macrophage alternative activation independent of Nrf2.
Barroso MV, Cattani-Cavalieri I, de Brito-Gitirana L, Fautrel A, Lagente V, Schmidt M, Porto LC, Romana-Souza B, Valença SS, Lanzetti M.
Bioorg Med Chem. 2017 Oct 15;25(20):5557-5568. doi: 10.1016/j.bmc.2017.08.026. Epub 2017 Aug 19.

Human Hepatocellular Carcinomas with a Periportal Phenotype Have the Lowest Potential for Early Recurrence after Curative Resection.
Désert R, Rohart F, Canal F, Sicard M, Desille M, Renaud S, Turlin B, Bellaud P, Perret C, Clément B, Lê Cao KA, Musso O.
Hepatology. 2017 May 12. doi: 10.1002/hep.29254. [Epub ahead of print]

2016

De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.
Mebarki S, Désert R, Sulpice L, Sicard M, Desille M, Canal F, Dubois-Pot Schneider H, Bergeat D, Turlin B, Bellaud P, Lavergne E, Le Guével R, Corlu A, Perret C, Coulouarn C, Clément B, Musso O.
Oncotarget. 2016 Jun 28;7(26):39026-39043. doi: 10.18632/oncotarget.9346.

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice
Amanda Poissonnier, Doriane Sanseau, Matthieu Le Gallo, Marine Malleter, Nicolas Levoin, Roselyne Viel, Lucie Morere, Aubin Penna, Patrick Blanco, Alain Dupuy, Florence Poizeau,Alain Fautrel, Julien Seneschal, Florence Jouan, Jerome Ritz, Edouard Forcade, Nathalie Rioux,Cecile Contin-Bordes, Thomas Ducret, Anne-Marie Vacher, Paul A. Barrow, Robin J. Flynn,Pierre Vacher, and Patrick Legembre
doi:10.1016/j.immuni.2016.06.028

Gene expression profiling of the tumor microenvironment in human intrahepatic cholangiocarcinoma.
Sulpice L, Desille M, Turlin B, Fautrel A, Boudjema K, Clément B, Coulouarn C.
Genom Data. 2016 Jan 15;7:229-32. doi: 10.1016/j.gdata.2016.01.012. eCollection 2016 Mar.
PMID:  26981414

 
Impact of stroma LOXL2 overexpression on the prognosis of intrahepatic cholangiocarcinoma.
Bergeat D, Fautrel A, Turlin B, Merdrignac A, Rayar M, Boudjema K, Coulouarn C, Sulpice L.
J Surg Res. 2016 Jun 15;203(2):441-50. doi: 10.1016/j.jss.2016.03.044. Epub 2016 Mar 26.
PMID:  27363654

 
Slice correspondence estimation using SURF descriptors and context-based search for prostate whole-mount histology MRI registration.
Guzman L, Commandeur F, Acosta O, Simon A, Fautrel A, Rioux-Leclercq N, Romero E, Mathieu R, de Crevoisier R.
Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1163-1166. doi: 10.1109/EMBC.2016.7590911.
PMID:   28268532

Mid-infrared fibre evanescent wave spectroscopy of serum allows fingerprinting of the hepatic metabolic status in mice.
Le Corvec M, Allain C, Lardjane S, Cavey T, Turlin B, Fautrel A, Begriche K, Monbet V, Fromenty B, Leroyer P, Guggenbuhl P, Ropert M, Sire O, Loréal O.
Analyst. 2016 Oct 24;141(22):6259-6269.
PMID: 27704067

2015

Prognostic and predictive values of oncogenic BRAF, NRAS, c-KIT and MITF in cutaneous and mucous melanoma.
Pracht M, Mogha A, Lespagnol A, Fautrel A, Mouchet N, Le Gall F, Paumier V, Lefeuvre-Plesse C, Rioux-Leclerc N, Mosser J, Oger E, Adamski H, Galibert MD, Lesimple T.
J Eur Acad Dermatol Venereol. 2015 Aug;29(8):1530-8. doi: 10.1111/jdv.12910. Epub 2015 Jan 26.

Excessive dietary linoleic acid induces proinflammatory markers in rat.
Marchix J, Choque B, Kouba M, Fautrel A, Catheline D, Legrand P.
J Nutr Biochem. 2015 Jul 30. pii: S0955-2863(15)00174-6. doi: 10.1016/j.jnutbio.2015.07.010. [Epub ahead of print]

Prostate whole-mount histology reconstruction and registration to MRI for correlating in-vivo observations with biological findings.
Commandeur F, Acosta O, Simon A, Mathieu R, Fautrel A, Gnep K, Haigron P, de Crevoisier R.
Conf Proc IEEE Eng Med Biol Soc. 2015;2015:2399-402. doi: 10.1109/EMBC.2015.7318877.

 
Transcriptomic Analysis of Trout Gill Ionocytes in Fresh Water and Sea Water Using Laser Capture Microdissection Combined with Microarray Analysis.
Leguen I, Le Cam A, Montfort J, Peron S, Fautrel A.
PLoS One. 2015 Oct 6;10(10)

2014

Comparative transcriptional profiling of human merkel cells and Merkel cell carcinoma
Nicolas Mouchel, nolwenn Coquart, Nicolas Lebonvallet, Christelle Le Gall-Lanotto, Ariane Mogha, Alain Fautrel, Nicolas Boulais, Brigitte Dreno, Ludovic Martin, Weiguo Hu, Marie-Dominique Galibert and Laurent Misery
Experimental dermatology 2014,23,922-941

Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma
Sulpice L, Rayar M, Turlin B, Boucher E, Bellaud P, Desille M, Meunier B, Clément B, Boudjema K, Coulouarn C
J Surg Res 2014 Nov 192(1) 117-23

Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages.
Gicquel T, Victoni T, Fautrel A, Robert S, Gleonnec F, Guezingar M, Couillin I, Catros V, Boichot E, Lagente V.
Clin Exp Pharmacol Physiol. 2014 Apr;41(4):279-86.

Overexpression of MLN51 triggers P-body disassembly and formation of a new type of RNA granules.
Cougot N, Daguenet E, Baguet A, Cavalier A, Thomas D, Bellaud P, Fautrel A, Godey F, Bertrand E, Tomasetto C, Gillet R.
J Cell Sci. 2014 Nov 1;127(21):4692-701

A spopntaneous KRT16 mutation in a dog Breed: a model for Human Focal Non epidermolytic Palmoplantar Keratoderma (FNEPPK)
Plassais J, Guaguère E, Lagoutte L, Guillory A, de Citres CD, Degorce-Rubiales F, Delverdier M, Vaysse A, Quignon P, Bleuart C, Hitte C, Fautrel A, Kaerle C, Bellaud P, Bensignor E, Queney G, Bourrat E, Thomas A, André C.
 J Invest Dermatol. 2014 Dec 18

2013
 
Gene expression profiling of the hyperplastic growth zones of the late trout embryo myotome using laser capture microdissection and microarray analysis.                              
Pierre-Yves Rescan , Jérome Montfort , Alain Fautrel, Cécile Rallière  and Véronique Lebret
BMC Genomics 2013 Mar 14;14;173

Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma
Sulpice L, Rayar M, Desille M, Turlin B, Fautrel A, Boucher E, Llamas-Gutierrez F,Meunier B, Boudjema K,Clément B, Coulouarn C
Hepatology 2013 jun 14 doi :10.1002/hep26577

Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade Cliomas
Marie de Tayrac, Stephan Saikali, Marc Aubry, Pascale Bellaud, Rachel Boniface, Véronique Quillien, Jean Mosser
PLOS one 2013 sept. Volume8 Issue 9

2012

The gene transfection properties of a lipophosphoramidate derivate with two phytanyl chains
Mattias Lingdberg, Nathalie Carmoy, Tony Le Gall, Aurore Fraix, Mathieu Berchel, Christophe Lorilleux , Helene Couthon-gourves, Pascale Bellaud, Alain Fautrel, Paul Alain Jaffres, Pierre Lehn, Tristan Montier
Biomaterials 33 2012 (6240-6253)

2011

Pentoxifylline aggraves fatty liver in obese and diabetic ob/ob mice. Possible role of increased intestinal glucose absorption and activation of hepatic ChREBP
Massart J, Robin MA, Noury F, Fautrel A, lettéron P, Bado A, Eliat P, Fromenty B
Inserm U991 Rennes, H2P2 platform, Prism platform
Br J Pharmacol. 2011 Jul 8

Il-1 and Il-23 Mediate Early Il17A Production in Pulmonary Inflammation Leading to Late Fibrosis
Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, Padova FD, Fick L, Charron S, Lagente V, Eberl G, Lebert M, Quesniaux V, Huaux F, Leite de Moraes M, Ryffel B, Couillin I.
CNRS UMR6218 Orléans, UMR8147 Paris, University Orléans, University Paris V, Inserm U991, H2P2 Platform, ...
PLoS ONE  August 2011 Vol. 6 Issue 8

Overexpression of active aurora-C kinase results in cell transformation and tumour formation.
Khan.J, Ezan F, Crémet JY, Fautrel A, Gilot D, Lambert M, Benaud C, Troadec MB, Prigent C.
PloS One 2011;6(10)

2010

Merkel Cell Polyomavirus Small Antigen mRNA Level is increased following in vivo UV Radiation
Ariane Mogha, Alain Fautrel, Nicolas Mouchet, Na Guo, Sébastien Corre, Henri Adamski, Eric Watier, Laurent Misery, Marie-Dominique Galibert
UMR CNRS 6061 ; Plateforme H2P2 ; Proclaim ; CHU rennes ; Université de Brest
PLoS ONE 2010 July vol.5

A three-dimensional digital segmented and deformable brain atlas of the domestic pig.
Saikali S., Meurice P., Sauleau P., Eliat PA., Bellaud P., Randuineau G., Vérin M., Malbert CH.
departement d'anatomie et cytologie pathologique CHU Rennes ; Plateforme H2P2 ;UMR SEHNA INRA ; PRISM
J. Neuroscience Methods. 2010 Aug 6

La microdissection laser : de la graine de colza à l'homme en passant par le poisson
Alain Fautrel, Pascale Bellaud, Roselyne Viel
Rev.Fr.Histotechnol.,2010, vol.23, n°1

2009

Ectopic Germinal Centers Are Rare in Sjogren's Syndrome Salivary Glands and Do Not Exclude Autoreactive B Cells
*Laetitia Le Pottier, *Valerie Devauchelle, **Alain Fautrel, *Capucine Daridon, *Alain Saraux, *Pierre Youinou, and *Jacques-Olivier Pers
*EA 2216 Brest, **INSERM U620, plate-forme Histo-pathologie IFR 140
The Journal of Immunology   Volume 182 / No. 6 / Mar 15, 2009

Chronic ethanol consumption lessens the gain of body weight, liver triglycerides and diabetes in obese ob/ob mice
Fromenty B1, Vadrot N, Massart J1, Turlin B1,2, Barri-Ova N, Letteron P, Fautrel A1,2, Robin MA1.
1- INSERM U620, 2 - plate-forme Histo-pathologie IFR 140
J Pharmacol Exp Ther. 2009 Jul 8.

Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed
Bathilde Auger1 · Cécile Baron1 · Marie-Odile Lucas1 ·Sonia Vautrin · Hélène Bergès · Boulos Chalhoub ·
Alain Fautrel2 · Michel Renard1 · Nathalie Nesi1
1 : UMR118 INRA le rheu ; 2 : Plate-forme H2P2
Planta 2009 sept 3

2008

Transcripts of ceruloplasmin but not hepcidin,both major iron metabolism genes, exhibit a decreaseing pattern along the portocentral axis of mouse liver
Marie-Bérengère Troadec a,f, Alain Fautrel b,c, Bernard Drénou d, Patricia Leroyer a,
Emilie Camberlein a, Bruno Turlin a,c,e, André Guillouzo b, Pierre Brissot a,f, Olivier Loréal a,
a INSERM U522, b INSERM U620, c IFR 140 Core HistoPathology Platform, d Haematology Department, E Muller Hospital, e Department of Anatomopathology, University Hospital Pontchaillou, f Liver Disease Unit, University Hospital Pontchaillou
Biochimica et Biophysica Acta 1782 (2008) 239–249

Pour cet article nous avons utilisé, sur la plateforme, les techniques de capture laser avec préparation d'ARN et d'hybridation in situ.

B-Cell phenotypical and transcriptional analysis in the salivary glands of patients with Sjogren's Syndrome
Laëtitia Le Pottier*, Capucine Daridon*, Alain Fautrel**, Martine Bonnaure-Mallet***, Pierre Youinou* et Jacques-Olivier Pers*
*EA 2216 Brest, **INSERM U620, plate-forme Histo-pathologie IFR 140, ***Equipe de Microbiologie, UPRES-EA 1254,
ADF, Vol 11 ; 24 ; 2008

Pour cet article nous avons utilisé, sur la plateforme, les techniques de capture laser après marquage immunofluorescent et préparation d'ARN pour QPCR

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo
A. Bessard 1, C. Fremin 1, F. Ezan 1, A. Fautrel 2, L. Gailhouste 1 and G. Baffet 1
1- INSERM U522, IFR 140, Hopital Pontchaillou, Universite´ de Rennes1, Rennes, France and
2 - Plate-forme d’Histo-Pathologie, IFR140, Universite´ de Rennes 1 CHU de Rennes, France
Oncogene (2008), 1–11

Pour cet article nous avons utilisé, sur la plateforme, les techniques de capture laser

 

Remerciements

Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis

Nicolas Matt, Norbert B. Ghyselinck, Isabelle Pellerin, Valérie Dupé

Developmental Biology 2008

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Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions

Tony Avril, Stephan Saikali, Elodie Vauleon, Anne Jary, Abderrahmane Hamlat, Marie De Tayrac, Jean Mossec, Véronique Quillien

Journal of Neuroimmunology  225 (2010) 22-33

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PNPLA1 mutations cause autosomal recessive congenital ichthyosis in Golden retriever dogs and humans,

Anaïs Grall, Eric Guaguère, Sandrine Planchais, Susanne Grond, Emmanuelle Bourrat, Ingrid Hausser, Christophe Hitte, Matthieu Le Gallo, Céline Derbois, Gwang-Jin Kim, Laëtitia Lagoutte, Frédérique Degorce-Rubiales, Franz Radner, Anne Thomas, Sébastien Küry, Emmanuel Bensignor, Jacques Fontaine, Didier Pin, Robert Zimmermann, Rudolf Zechner, Mark Lathrop, Francis Galibert, Catherine André, Judith Fischer,

Nature Genetics (2012), 44(2):140-147, doi:10.1038/ng.1056

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Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis

Laurence Amiot, Nicolas Vu, Michel Rauch, Annie L’Helgoualc’h, Frédéric Chalmel, Hugues Gascan, Bruno Turlin, Dominique Guyader, Michel Samson

Journal of Hepatology 2013 vol. xxx j xxx–xxx

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Inactivation of the Celf1 Gene that Encodes an RNABinding Protein Delays the First Wave of Spermatogenesis in Mice

Marie Cibois, Gaella Boulanger, Yann Audi, Luc Paillard, Carole Gautier-Courteille

PLOS ONE October 2012 | Volume 7 | Issue 10 | e46337

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Involvement of ITIH5, a Candidate Gene for Congenital Uterovaginal Aplasia (Mayer-Rokitansky-Kuster-Hauser Syndrome), in Female Genital Tract Development

KARINE MORCEL,TANGUY WATRIN, FREDERIQUE JAFFRE, STEPHANE DESCHAMPS, FRANCIS OMILLI, ISABELLE PELLERIN,JEAN LEVEQUE, AND DANIEL GUERRIER

Gene Expression, Vol. 15, pp. 1–100

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NOTCH, a new signaling pathway implicated in holoprosencephaly

Valerie Dupe, Lucie Rochard, Sandra Mercier, Yann Le Petillon, Isabelle Gicquel, Claude Bendavid, Georges Bourrouillou, Usha Kini, Christel Thauvin-Robinet, Timothy P. Bohan, Sylvie Odent, Christele Dubourg and Veronique David

Received October 1, 2010; Revised November 26, 2010; Accepted December 23, 2010 Genetics

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Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat

Fanny Lemarié, Erwan Beauchamp, Stéphanie Dayot, Cécile Duby, Philippe Legrand, Vincent Rioux

PLOS ONE | DOI:10.1371/journal.pone.0133600 July 21, 2015

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NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis

Muhammad I. Arshad, Michel Rauch, Annie L’Helgoualc’h, Valerie Julia, Maria C. Leite-de-Moraes, Catherine Lucas-Clerc, Claire Piquet-Pellorce and Michel Samson

Eur. J. Immunol. 2011. 41: 2341–2348

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TRAIL, but not FasL and TNFα, regulates IL-33 expression in hepatocytes during acute hepatitis in mice.

Muhammad Imran Arshad, Claire Piquet-Pellorce, Annie L’Helgoualc’h, Michel Rauch, Solène Patrat-Delon, Frédéric Ezan, Catherine Lucas-Clerc, Sabrina Nabti, Agnès Lehuen, Francisco Javier Cubero, Jean-Philippe Girard, Christian Trautwein and Michel Samson.

Hepatology. 2012 Dec;56(6):2353-62. doi: 10.1002/hep.25893. Epub 2012 Sep 24.

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IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology

Muhammad I. Arshad, Claire Piquet-Pellorce and Michel Samson

Liver Int. 2012 Sep;32(8):1200-10. doi: 10.1111/j.1478-3231.2012.02802.x. Epub 2012 Apr 24

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The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease

Grégoire Michaux, Dominique Massey-Harroche, Ophélie Nicolle, Marion Rabant, Nicole Brousse, Olivier Goulet, André Le Bivic, Frank M Ruemmele

Biol Cell. 2015 Nov 3. doi: 10.1111/boc.201500034.

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Hypogonadism Associated with Cyp19a1 (Aromatase) Posttranscriptional Upregulation in Celf1 Knockout Mice

Gaella Boulanger, Marie Cibois, Justine Viet, Alexis Fostier, Stéphane Deschamps, Sylvain Pastezeur, Catherine Massart, Bernhard Gschloessl, Carole Gautier-Courteille, Luc Paillard

Molecular and Cellular Biology September 2015 Volume 35 Number 18

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INFLUENZA VIRUS INFECTION INDUCES IL-33 IN MOUSE LUNGS.

Ronan Le Goffic, Muhammad Imran Arshad, Michel Rauch, Annie L’Helgoualc’h, Bernard Delmas, Claire Piquet-Pellorce and Michel Samson.

AJRCMB Articles in Press. Published on June 3, 2011 as doi:10.1165/rcmb.2010-0516OC

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Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system

Leslie Ratié, Michelle Ware, Hélène Jagline, Véronique Davi1, and Valérie Dupé

ORIGINAL RESEARCH ARTICLE published: 18 December 2014 doi: 10.3389/fnana.2014.00158

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Expression Screening ofCancer/TestisGenes in Prostate Cancer IdentifiesNR6A1 as a NovelMarker of disease Progression and Aggressiveness

Romain Mathieu, Bertrand Evrard,Gaelle Fromont, Nathalie Rioux-Leclercq,
Julie Godet, Xavier Cathelineau, François Guille, Michael Primig, and Frederic Chalmel

The Prostate 73:1103^1114 (2013)

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Superoxide production pathways in aortas of diabetic rats: beneficial effects of insulin therapy and endurance training

L. Malarde, A. Rebillard, S. Le Douairon-Lahaye, S. Vincent, M. S. Zguira, S. Lemoine-Morel, A. Gratas-Delamarche, C. Groussard

Mol Cell Biochem DOI 10.1007/s11010-013-1932-z